Only PENTASA® delivers 5-ASA from top to bottom
PENTASA moisture-activated microspheres ensure reliable delivery throughout the
small and large intestine1-5
- Release of 5-ASA from PENTASA is independent of pH.
- The moisture-activated MOA ensures that PENTASA will begin delivering mesalamine
in the duodenum.6
- 5-ASA is released at a virtually constant rate from the duodenum to the rectum,
until essentially all the available drug is delivered1,2,6,7
Moisture-activated PENTASA provides complete top-to-bottom coverage
- Only moisture-activated, controlled-release PENTASA delivers 5-ASA to the duodenum,
jejunum, ileum, terminal ileum, proximal colon, distal colon, and rectum. 6,7
Other 5-ASA products deliver to limited areas of the intestine
- pH-dependent, delayed-release Asacol delivers 5-ASA only to the distal ileum, colon
and rectum.7
- Colazal delivers 5-ASA to the colon following bacterial cleavage of the azo bond.6,12
Next: Dosing
Asacol® is a registered trademark of Procter & Gamble Pharmaceuticals.
Colazal® is a registered trademark of Salix Pharmaceuticals.