Taking PENTASA

PENTASA 500-mg Capsules Bring Reliable Drug Delivery to Your Small and Large Intestine

Only PENTASA features a water-based mesalamine delivery system. This water-based delivery system is designed to deliver mesalamine throughout your small and large intestine.

Other oral mesalamine drugs work differently. They may instead rely on your digestive system having the right levels of acid (pH) or bacteria to deliver the mesalamine into your colon.

PENTASA 500-mg Capsules May Relieve Your Symptoms with Fewer Capsules

PENTASA helps to bring your symptoms under control. In a clinical study, PENTASA significantly reduced the severity of the most common signs and symptoms of ulcerative colitis (compared with a sugar pill), including:

  • Bleeding from the rectum
  • Stomach cramps
  • The urge to go to the bathroom
  • The number of trips to the toilet each day

PENTASA 500-mg capsules provide symptom control and relief with only 8 capsules a day. That’s half the number of capsules compared with the 250-mg formulation.

How to Take PENTASA Capsules

The recommended dosage of PENTASA 500-mg capsules is two capsules, taken four times a day. When taking PENTASA 250-mg capsules, the recommended dosage is four capsules, taken four times a day.

Ask your doctor when the best time is to take PENTASA each day.

Important Safety Information

  • PENTASA is approved for the induction of remission and for the treatment of mildly to moderately active ulcerative colitis.
  • PENTASA is generally well tolerated and most side effects are mild. In worldwide clinical studies, the most common side effects were diarrhea, headache, nausea, abdominal pain, upset stomach, vomiting, and rash. As with other medications, some serious side effects may occur. You should not take PENTASA if you are allergic to salicylates, such as aspirin. Tell your doctor if you have problems with your liver or kidneys. While taking PENTASA, visit your doctor periodically. If you have any questions about PENTASA, please talk to your doctor.